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Best compilation and packaging option for profiling

Hi,

My packages are compiled with the following options :
- AnyCPU
- Release
- Optimize flag

And when packaging is done, all PDB are removed.

I can adapt those as I want, but I would like to know what are the best options to set before.

Also I would like to have an overview of which option can impact what.

For example:
- if I set Optimize mode, what does it change when profiling and profiling results ?
- if I compile using release, what does it change when profiling and profiling results ?
- ...

Thanks

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